The Museum was founded as the West Texas Museum in 1929, shortly after Texas Technological College was chartered in 1925. In the 1990s the site was jointly operated by TTU and the Texas Parks & Wildlife Department as Lubbock Lake Landmark State Historical Park. During that time, several new buildings were constructed including the Robert A. "Bob" Nash Interpretive Center and the Quaternary Research Center. In 1999, the state historical park was fully transferred to Texas Tech University under the supervision and care of the Museum of TTU, and returned to the name Lubbock Lake Landmark.