Find a home away from home at our Hampton Inn & Suites Orlando/Downtown South-Medical Center. This welcoming hotel is within walking distance to Orlando Regional Medical Center, UF Health Cancer Center and Arnold Palmer Hospital for Children. Just a few blocks from the Amtrak line, it’s easy to get around town from our hotel. Make your stay easy with free hot breakfast every morning or if you’re pressed for time, grab one of our Hampton’s On the Run™ Breakfast Bags, available Monday through Friday. All our rooms feature two queen or one king-sized Hampton clean and fresh bed® and free WiFi. Unwind with your favorite shows on the 39-inch HDTV.